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PurposeTo present new information on the semiology and short‐term evolution of seizures associated with primary brain tumors (PBTs) in a prospective study.
MethodsThis study is a section of the PERNO study – Project of Emilia Romagna Region on Neuro‐Oncology, the main aim of which is to collect prospectively all cases of PBTs occurring in the Emilia‐Romagna region, northeast Italy (3,983,346 population)...
PurposeTo analyze the clinical outcome of epilepsy surgery in children, and to identify the factors related with a favorable seizure control among several presurgical, surgical and postsurgical variables.
MethodsOne‐hundred twenty children, younger than 16 years (69 male and 51 female), operated on for medically refractory focal epilepsy at the “C.Munari” Epilepsy Surgery Center of the Niguarda Hospital...
The Commission for Epilepsy Surgery of the Italian League Against Epilepsy (LICE) presents an overview of the techniques and methodologies of presurgical evaluation and of the surgical treatment of epilepsies. This overview is the result of the experience developed in the past years in the major Italian centers where programs of epilepsy surgery have been established, and it has the aim of offering...
PurposeThe term “fixation off sensitivity” (FOS) was proposed by Panayiotopoulos to describe epilepsy/electroencephalography (EEG) changes evoked by the suppression of central vision and fixation. The EEG pattern usually consists of spike/polyspike and waves localized in occipital regions. FOS occurs mainly in children with idiopathic occipital partial epilepsies and rarely in adults. In this retrospective...
The Italian League Against Epilepsy Commission Guidelines Subcommittee on Status Epilepticus (SE) has published an article on the management of SE in adults, and now presents a report on the management of convulsive status epilepticus (CSE) in children, excluding the neonatal period. Children's greater susceptibility than adults to epileptic seizures results from many factors. Earlier maturation of...
Reports of childhood epilepsies in temporal association with vaccination have had a great impact on the acceptance of vaccination programs by health care providers, but little is known about this possible temporal association and about the types of seizures following vaccinations. For these reasons the Italian League Against Epilepsy (LICE), in collaboration with other Italian scientific societies,...
PurposeAbsence epilepsy with onset before age 4 years, or early onset absence epilepsy (EOAE), has been rarely reported, and children with onset in the first year of life are considered almost exceptional. We aimed to report the clinical and electrophysiologic features of a cohort of children with absence epilepsy starting within the first year of life.
MethodsThis was a multicenter study including...
The Italian League Against Epilepsy has issued evidence‐based guidelines to help practicing physicians in their decision to stop or withhold antiepileptic drugs (AEDs) in patients achieving a prolonged period of seizure freedom. Six adult and two child neurologists, divided into four pairs, critically appraised 128 published reports and provided graded recommendations answering 15 key questions: length...
PurposeEpilepsy is a neurologic disorder with major social impact. Surgery is a valuable option in patients who are not responding to antiepileptic drugs. The literature reports demonstrate that a proportion ranging from 40 to 100% of patients with epilepsy achieve seizure remission after surgery. A presurgical evaluation (clinical and instrumental) must be performed in all patients with drug‐resistant...
PurposeThe aim of this study was to evaluate the long‐term cognitive outcome in children with continuous spikes and waves during slow wave sleep (CSWS syndrome).
MethodsWe reviewed the neuropsychological tests of 25 children diagnosed with CSWS between 1987 and 2010 and with a mean follow‐up of 13.5 years.
Key FindingsCognitive performances worsened during CSWS in virtually all patients. Seven patients...
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